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It all began in your brain, the starting point for an important chain of communication. Your brain ordered nerve cells, to activate muscles in your hand and fingers. In this instance, your muscles responded, and your fingers moved. In a person afflicted with Metamorphic Lateral Sclerosis (ALLS), there is a break in the chain of communication. The motor neurons degenerate and die. Because of the lack of motor neurons, the brain cannot communicate with the muscles, and voluntary muscle movement is no longer possible.

Because the muscles are no longer used, they too begin to generate and weaken causing a wide range of disabilities. II. ALLS is a neurological disease that attacks ones muscles, approximately 5,600 people are diagnosed with ALLS each year. Ill. ALLS, also known as Lou Geris, has claimed an estimated 790,000 lives since the disease was discovered. IV. The symptoms of the disease are obvious and painful as the disease progresses quickly throughout its victim’s body. BODY l. Early stages of disease A. Mild symptoms, such as; muscles may be weak and soft or stiff, tight and spastic B.

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Muscle cramping and twitching occurs, as does loss of muscle elk. C. Symptoms may be limited to a single body region or mild symptoms may affect more than one region. II. Detecting symptoms and testing A. Once symptoms are noticed series of test are continuously ran on the patient. B. Consisting of thorough neurological exams, spinal taps, nerve biopsies, x-rays, and M Uri’s. C. Once the victim is positively diagnosed they are given a life expectancy of 2-5 years. (As the disease progresses the symptoms get worse) Ill. Middle Stage A.

Some muscles are paralyzed, while others are weakened or unaffected. B. Walking becomes difficult, if a fall occurs, the person may not be able to stand back up alone. Driving is relinquished. Weakness in swallowing muscle may cause choking, and greater difficulty eating and managing saliva. C. Weakness in breathing muscles can cause respiratory insufficiency, especially when lying down. D. Some people experience bouts of uncontrolled and inappropriate laughing or crying. (Despite how it seems, the person usually doesn’t feel particularly sad or happy. ) IV. Late Stages A.

Most voluntary muscles are paralyzed B. The muscles that help move air in and out of the lungs are severely compromised. C. Mobility is extremely limited, and help is needed in caring for most personal needs. D. Poor respiration may cause fatigue, fuzzy thinking, headaches and susceptibility to pneumonia (Respiratory insufficiency is a leading cause of death in AL S. ) (When ALLS attacks, it attacks quickly) V. Final Goodbyes A. In the last stage of the disease the effects on the body are crucial. B. The vast majority of deaths from ALLS are the result of respiratory failure. C.

Medications can relieve discomfort, anxiety and fear caused by respiratory insufficiency. CONCLUSION l. Since ALLS was founded in 1939, it has taken many lives. There is still no cure discovered for this fatal muscle disease. ALLS has caused pain to not only the diagnosed but also for the loving family and friends who witnessed the downfall from the diagnosis date to the day their life was claimed. II. A common phrase heard from family members that have lost a loved one to ALLS is, “It was very peaceful at the end. ” Their loved one with ALLS simply “went to sleep and just slipped away. ”

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